产品货号：
Z22180
中文名称：
NOX1抗体
英文名称：
Anti-NOX1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-NOX1 Antibody |
| 指标别名 | GP91 2;Mitogenic oxidase 1;MOX 1;MOX1;NADPH oxidase 1;NOH 1;NOH1;NOX 1;NOX1 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | IHC,WB |
| 基因名称 | NOX1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence in the middle region of human NOX1(354-374aa,HIRAAGDWTENLIRAFEQQYS). |
| 实际分子量 | 65KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | NOX1(NADPH OXIDASE 1),also known as NOH1,MOX1 or GP91-2,is an enzyme that in humans is encoded by the NOX1 gene.It is also a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes,gp91phox.The NOX1 gene is mapped to Xq22.1.NOX1 was expressed in colon,prostate,uterus,and vascular smooth muscle,but not in peripheral blood leukocytes.The deduced 564-amino acid NOX1 protein,which is 58% identical to CYBB,contains 6 membrane-spanning regions,conserved flavin and pyridine nucleotide-binding sites,and histidines possibly involved in heme ligation.Overexpression of MOX1 in NIH 3T3 cells increased superoxide generation and cell growth.Cells expressing MOX1 had a transformed appearance,showed anchorage-independent growth,and produced tumors in athymic mice.Disruption of either Nox1 or Nox2 significantly delayed progression of motor neuron disease in these mice.However,50% survival rates were enhanced significantly more by Nox2 deletion than Nox1 deletion. |
| Uniprot ID | Q9Y5S8 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | NADPH oxidase 1 |
| 蛋白名全称 | NADPH oxidase 1(NOX-1) |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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